Stipkovits L, Varga Z, Laber G & Böckmann J
A comparison of the effect of tiamulin hydrogen fumarate and tylosin tartrate on mycoplasmas of ruminants and some animal ureaplasmas.>
Vet Microbiol, 9(2): 147-153, 1984
ISSN: 0378-1135 Veterinary Microbiology (PubMed)
Abstract
The in vitro efficacy of tiamulin was compared to that of tylosin against 7 bovine, 7 ovine and 3 caprine mycoplasma strains isolated from various organs and belonging to different species, as well as 7 ureaplasma strains cultured from cattle, sheep, swine, chickens and turkeys. The minimal mycoplasmacidal concentrations of tiamulin varied between 0.01 and 10.0 micrograms ml-1, while tylosin proved to be active in concentrations of 0.5 and 100.0 micrograms ml-1. Five of 17 mycoplasma strains showed identical sensitivities to both antibiotics while all other strains, including the ureaplasmas, were sensitive to tiamulin at concentrations 5-5000-times lower than tylosin.