Webster JC & Cidlowski JA
Mechanisms of Glucocorticoid-receptor-mediated Repression of Gene Expression.

Trends Endocrinol Metab, 10(10): 396-402, 1999
ISSN: 1043-2760 Trends in Endocrinology and Metabolism (PubMed)

Abstract
It is hoped that this review will give the reader a taste of some of the mechanisms used by the glucocorticoid receptor to repress gene function. These mechanisms include direct binding to DNA, antagonism of other transcription factor families and sequestration of necessary cofactors. Each of these mechanisms, and others, are discussed.