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Vercammen F, De Deken R & Maes L
Prophylactic treatment of experimental canine babesiosis (Babesia canis) with doxycycline.

Vet Parasitol, 66(3-4): 251-255, 1996
ISSN: 0304-4017 Veterinary Parasitology (PubMed)

Abstract
Doxycycline provided satisfactory prophylaxis against experimental infection with a highly pathogenic strain of Babesia canis. Rectal temperature, parasitaemia, packed cell volume and serology were monitored for evaluation of the prophylactic effect. Although a daily dose of 5 mg kg-1 of doxycycline did not completely prevent clinical disease, symptoms remained moderate and a full recovery was obtained within 1 week. At a dose of 20 mg kg-1 day-1 no clinical symptoms were observed, but asymptomatic infection could not be ruled out.

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